SCIENCE-JOBS-DE

PhD position in redox control of metabolism (Kaiserslautern, Germany)

The department of Cell Biology at the University of Kaiserslautern invites applications from highly motivated PhD students to work on an exciting project aimed at understanding the redox regulation of cellular metabolism.

This project will make use of novel, ultra-sensitive, genetically-encoded hydrogen peroxide sensors, which allow real-time measurements of cellular hydrogen peroxide, with sub-cellular compartment specificity in intact, living cells. We will combine these probes with the extensive array of genetic tools available in the yeast S. cerevisiae, with the aim to gain fundamental new insights. For examples of similar recent work, see references below.

We are an English-speaking, international laboratory with a friendly and productive work atmosphere and state-of-the-art equipment. Kaiserslautern is located in the famous Palatinate forest, with a very affordable cost-of-living and an international population.

Applicants must have a Master degree or equivalent in Biology, Biochemistry, Biophysics or related fields. We expect excellent oral and written communication skills in English and an enthusiasm for science.  Your application, together with a short CV, copies of Masters and high school certificates and contact details of at least one referee should be sent as a PDF to:

bruce.morgan@biologie.uni-kl.de


For further information please contact:

Dr. Bruce Morgan
Cellular Biochemistry, University of Kaiserslautern,
Erwin-SchrÓ§dinger-Str. 13, 67663 Kaiserslautern
Tel. +49 (0) 631 205 2885




References:
Morgan B, Ezerina D, Amoako T, Riemer J, Seedorf M and Dick TP. Multiple glutathione disulfide removal pathways mediate cytosolic redox homeostasis. Nat Chem Biol. 2013; 9:119-125.

Kojer K, Bien M, Gangel H, Morgan B, Dick TP and Riemer J. Glutathione redox potential in the mitochondrial intermembrane space is linked to the cytosol and impacts the Mia40 redox state. EMBO J. 2012; 31(14):3169-82.

Morgan B, Sobotta MC and Dick TP. Measuring EGSH and H2O2 with roGFP2-based probes. Free Radic Biol Med. 2011; 51(11):1943-51.

Dr. Bruce Morgan
morgan@bio.uni-kl.de
University of Kaiserslautern
Kaiserslautern, Germany