SCIENCE-JOBS-DE

Research and Teaching Fellow (PhD Position) (subject to personal qualification employees are remunerated according to salary group E 13 TV-L) (Dresden)

At TU Dresden, DFG Center for Regenerative Therapies Dresden -
Cluster of Excellence (CRTD), the Chair of Molecular and Cellular
Immunology - Focus Immunoregulation (Prof. Dr. Karsten Kretschmer)
is looking for a highly motivated and talented

Research and Teaching Fellow (PhD Position)
(subject to personal qualification employees are remunerated according to salary group E 13 TV-L)

to join our team, with 50 to 65 % of the fulltime weekly hours. The position
is available starting as soon as possible. We offer a contract for three
years. The period of employment is governed by § 2 Fixed Term Research
Contracts Act (Wissenschaftszeitvertragsgesetz - WissZeitVG). The
Position will give you an excellent chance for further academic qualification
(e.g. PhD).
The research interest of our group focuses on molecular and cellular
pathways that govern the generation, lifestyle and function of Foxp3+
regulatory T (Treg) cells, which play an essential role in maintaining
immune homeostasis in mice and men. A particularly striking example of
Foxp3+ Treg cell function that restrains destructive tissue-specific
autoimmunity is our recent observation that acute Treg cell ablation in the
NOD mouse model of human type 1 diabetes unleashes overt autoimmune
diabetes within days (Petzold et al., J Diabetes Res 2013). Conversely,
Treg cells represent exciting gain-of-function targets in clinical settings of
unwanted immune responses, such as autoimmunity, allergies and
transplant rejection.
Position and Requirements:
The PhD position we offer is part of a project in which we aim to
investigate the molecular and epigenetic mechanisms underlying the
development of Foxp3+ Treg cell sublineages. In this context, a particular
focus is placed on exploring the possibility that different Treg cell
subphenotypes exert specialized effector functions in the control of
unwanted immunity, such as organ-specific autoimmunity (webpage:
http://www.crt-dresden.de/research/crtd-core-groups/kretschmer.html).
We aim at attracting the best talent in the respective research fields and expect the following: an outstanding masters university degree (or
equivalent) in Biology, Biomedicine or related field of science; experience in immunology, flow cytometry, gene-targeted and autoimmune mouse models, cell culture and molecular/biochemical methods; ability to work in an international team; inter- and multidisciplinary thinking; high motivation; an integrative and cooperative personality with excellent communication and social skills; fluency in English - written and oral.
Applications from women are particularly welcome. The same applies to
people with disabilities.
Application Procedure
Your application should include: 1. Cover letter, indicating current and future research interests and career goals; 2. description of research experience and accomplishments, including summary of previous research done during your master thesis (max. 2 pages); 3. list of publications, if available; 3. CV, including copies of degree certificates and transcript of grades (i.e. the official list of coursework including your grades); 4. two letters of recommendation or contact information for two references, including current supervisor.
Please submit your application by 25.03.2015 (stamped arrival date applies) preferably by email as a single pdf document (using
"surname_firstname.pdf") to silvia.palme@tu-dresden.de (Please note:
We are currently not able to receive electronically signed and encrypted data.) or via central mail service to the following address: TU Dresden, CRTD, Frau Silvia Palme, Fetscherstr. 105, 01307 Dresden, Germany. Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.


Silvia Palme
silvia.palme@tu-dresden.de
TU Dresden, DFG Center for Regenerative Therapies Dresden -  Cluster of Excellence (CRTD),  Chair of Molecular and Cellular  Immunology - Focus Immunoregulation
Dresden.