One position involves basic and translational work on innate immunity to positive-strand RNA viruses. A novel transgenic mouse model we recently developed will be used along with cell culture systems to investigate mechanisms of viral nucleic acid sensing by pattern-recognition receptors such as MDA5, in translational efforts to achieve broad-spectrum protection against microbial pathogens, and to decipher roles of the innate immune system in autoimmunity. Another position involves our ongoing studies of HIV-1 interactions with host cell proteins, including dependency and restriction factors. Applications of site-specific gene targeting to HIV cure are also of interest. For each position, a strongly motivated individual with a relevant Ph.D. degree is sought. Experience in virology, host-pathogen interactions, innate immunity, bioinformatics, or mouse modeling will be valued. Denver and Colorado’s Front Range provide spectacular year-round quality of life. Send C.V. and key publications via email (eric.poeschla@ucdenver.edu) to Dr. Eric Poeschla, Tim Gill Endowed Research Chair and Chief of Infectious Diseases, Anschutz Medical Campus, University of Colorado School of Medicine, Aurora CO 80045. Headline your email “Postdoctoral Fellowship Application.”

Don't forget to mention Naturejobs when applying.

Employer:University of Colorado Anschutz Medical Campus

Location:Aurora, CO, United States

Expires:July 31, 2015

Job type:Postdoctoral

Salary:Unspecified

Qualifications:Postgraduate - Doctorate/PhD

Employment type:Permanent

Job hours:Full-time

 

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PhD scholarships in synthetic biology tools for cell factory development : Copenhagen, Denmark

The section for Synthetic Biology Tools for Yeast (SBTY) at the Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) is expanding, and currently looking for talented and motivated PhD students to join our expert group working on synthetic biology tools.

In SBTY you will be part of a young international team headed by Prof. Jay D. Keasling, developing novel technology for the yeast engineering and synthetic biology community, emphasizing on basic research, with a strong drive towards application and improvement of the translational efforts at DTU Biosustain.

Job description
Your key responsibilities will be to develop and validate synthetic biology tools in order to support the DTU Biosustain mission to speed strain i) design, ii) building and iii) screening processes of new cell factories for chemical production. This includes advanced DNA assembly and genome engineering methods and development of genetic circuits and biosensors for high-throughput screening of chemical production or regulatory control of metabolic pathways of interest to DTU Biosustain. The position in SBTY will include an exchange research stay at the Joint BioEnergy Institute (JBEI.org) in Emeryville, California (US).

Qualifications
Mandatory requirements:

• Master's degree in engineering, biochemistry, biotechnology or a similar degree with an academic level equivalent to the master’s degree
• Good communication skills in English, both spoken and written
• Systematic and targeted work manners
• Good analytical skills and the ability to work both independently and as part of a team
• Strong work ethic and motivation to succeed within a competitive research field
• A strong motivation to work on biosustainable solutions at the interface of industry and academia

Preference is given to candidates with experience in:

• Microbial cell cultivation
• Understanding of yeast genetics
• Omics-based technologies and data analysis
• Molecular biology and metabolic engineering of yeast

Approval and Enrolment
The scholarships for the PhD degree are subject to academic approval, and the candidates will be enrolled in one of the general degree programs of DTU. For information about the general requirements for enrollment and the general planning of the scholarship studies, please see the DTU PhD Guide.

Assessment
The assessment of the applicants will be made by Scientific Director Jay D. Keasling and Co-Principal Investigator Michael K. Jensen.

We offer
DTU Biosustain is a DTU research center and is on par with a traditional academic university department, but without an educational mission. Besides its basic research in bioengineering, DTU Biosustain is also aiming at innovation by developing new technologies and transferring knowledge to industry for the benefit of society. The DTU Biosustain is therefore organized to operate at the interphase of basic and translational research.

We offer an interesting and challenging job in an international environment focusing on research and innovation, which contribute to enhancing the economy and improving social welfare. We strive for academic excellence, collegial respect and freedom tempered by responsibility. The Technical University of Denmark is a leading technical university in northern Europe and benchmarks with the best universities in the world.

Salary and appointment terms
The salary and appointment terms are consistent with the current rules for PhD students. The period of employment is 3 years. The place of work will be at DTU Biosustain, Kogle Allé 6, Hørsholm.

Further information
Further information may be obtained from Scientific director Jay D. Keasling (jaykea@win.dtu.dk)and Co-Principal Investigator Michael K. Jensen (mije@biosustain.dtu.dk).

Please do not send applications to this e-mail address, instead apply online as described below.

You can read more about DTU Biosustain on www.biosustain.dtu.dk

Application
Please submit your online application no later than 1 July 2015. Apply online at www.career.dtu.dk.

Applications must be submitted as one pdf file containing all materials to be given consideration. To apply, please open the link "Apply online," fill in the online application form, and attach a*ll your materials in English in one pdf file*. The file must include:

• A letter motivating the application (cover letter)
• Curriculum vitae
• Grade transcripts and BSc/MSc diploma
• Excel sheet with translation of grades to the Danish grading system (see guidelines and excel spreadsheet here http://www.dtu.dk/english/Education/phd/Applicant/Pre_acceptance-1-)

Candidates may apply prior to obtaining their master's degree, but cannot begin before having received it.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

DTU is a technical university providing internationally leading research, education, innovation and public service. Our staff of 5,700 advance science and technology to create innovative solutions that meet the demands of society; and our 10,000 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government, and public agencies.

…

Don't forget to mention Naturejobs when applying

Employer:Technical University of Denmark (DTU)

Website:http://www.dtu.dk/english

Location:Copenhagen, Denmark

Expires:July 01, 2015

Job type:PhD Studentship

Salary:Unspecified

Qualifications:Postgraduate - Master's degree

Employment type:Contract

Job hours:Full-time