In this project the master student will use our bacterial surface display system to display catalytically active enzymes on the surface of E. coli cells. Clonal populations of cells shall then be produced in picoliter aqueous droplets in oil or in alginate beads. Using suitable fluorescence based assays, cells displaying highly active enzymes or enzymes with advantageous properties will be sorted and will be further characterized.

The work involves a broad spectrum of state-of the-art techniques

including random mutagenesis, cloning, microbial fermentation, enzyme

assays and technology development.

Aim of the project is the generation of an improved cellulase and the

amelioration of the E. coli host cells. The project will be supervised

directly by Prof. Dr. Georg Lipps.

The University of Applied Sciences Northwestern Switzerland offers

modern and well-equipped laboratories and is situated in one of the most prominent centres of the Life Sciences Industry. Basle is located in the vivid trinational region (Switzerland, Germany, and France) in a beautiful landscape.

Please send your enquiries or your application including your bachelor degree diploma by email to:

Prof. Georg Lipps

University of Applied Sciences Northwestern Switzerland

georg.lipps@fhnw.ch

Georg Lipps

georg.lipps@fhnw.ch

Fachhochschule Nordwestschweiz

Basel (Schweiz)

Ansprechpartner: Georg Lipps (georg.lipps@fhnw.ch)