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Postdoctoral Fellow - Cell Sciences & Technology (Pre-Pivotal and Pivotal Drug Substance Process Development): Cambridge, MA & Thousand Oaks, CA, MA, United States

The Amgen Postdoctoral Program is committed to providing future scientists with an enriching environment to inspire innovation that will contribute to the development of human therapeutics.

This role will work in the Cell Sciences & Technology group within Amgen’s Pre-Pivotal and Pivotal Drug Substance Process Development organization. The position will work in a dynamic team environment to understand the connections between mammalian cell culture bioreactor process factors, cellular status patterns, and product profiles by utilizing state-of-art systems biology data integrating and modeling techniques.

The position will design and support a project that combines both data-driven and mechanism-driven modeling techniques to identify novel engineering targets/strategies for cell culture productivity improvement and product quality control in process development.

This project will occur in two phases in two locations: 1) multi-omics (transcript-, prote-, metabol-, and flux-omics) data collection and integration for current bioreactor projects (AMA: Cambridge, MA) and 2) data-driven, mechanism-based in-silico modeling to identify targets for productivity improvement and product quality control (ATO: Thousand Oaks, CA). The assignment length is expected to be 2-3 years.

Basic Qualifications
PhD at the time of appointment

Preferred Qualifications
PhD in Life Sciences or Engineering
Experience with cell culture/fermentation in an academic and/or pharmaceutical research setting
Experience in bioinformatics data analysis workflows using both software (ex. OmicSoft Array Suite) and computer programming environments (ex. Python, R, Perl, or equivalent)

Experience with experimental design and statistical data analysis using software such as JMP, SAS, or R
Strong scientific track record through either published or accepted papers in peer-reviewed journals
Demonstrated ability to independently identify, develop and implement scientific solutions to practical problems.
Demonstrated in-depth knowledge of laboratory equipment and operations
Demonstrated communication and scientific writing skills
Ability to execute projects as part of a team or independently

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Only candidates who apply via www.careers.amgen.com will be considered. Please search the database by position title or 34390BR. Or simply click on the link below to access the position directly.

https://amgen.wd1.myworkdayjobs.com/job/Cambridge/Postdoctoral-Fellow—-Cell-Sciences—-Technology_34390BR-1

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Employer:Amgen

Website:http://www.amgen.com/

Location:Cambridge, MA & Thousand Oaks, CA, MA, United States

Expires:February 02, 2016

Job type:Postdoctoral

Salary:Unspecified

Qualifications:Postgraduate - Doctorate/PhD

Employment type:Permanent

Job hours:Full-time