The group of Alexander Bird at the Max Planck Institute for Molecular Physiology (Dortmund) is looking for highly motivated PhD students interested in investigating of the function and regulation of microtubule networks in mammalian systems. Microtubules are required for various functions in cells, among them cell division and cell migration. Misregulation of microtubule dynamics and stability is thought to contribute to cancer progression by promoting chromosomal instability in mitosis, and potentially also by misregulation of cell migration promoting tumor cell invasion. We investigate the mechanisms of microtubule-related cellular functions in human cancer cell lines, as well as mouse embryonic stem cells, using a combination of novel genetic techniques, advanced live-cell fluorescence microscopy, and quantitative interaction proteomics.

A background and familiarity with molecular biology is required for this position. No specific experience with any techniques is required, but previous experience in fluorescence microscopy, mammalian cell culture, and/or cloning/DNA modification techniques is preferred. Most importantly, the applicant must be enthusiastic with a developed ability to think critically, as well as to read, interpret, and apply scientific literature to the project.

For more information on projects areas and previous work please visit our website: http://www.mpi-cbg.de/~bird

Applicants should email a CV, a short summary of previous research experience, and names of at least 2 references that may be contacted to alex.bird@mpi-dortmund.mpg.de

Alexander Bird

alex.bird@mpi-dortmund.mpg.de

Max Planck Institute of Molecular Physiology

Dortmund, Germany