The successful applicant will study how dysregulation of protein homeostasis contributes to the development of myeloid malignancies. To this end, genetic screens using custom shRNA and CRISPR libraries and mass spectrometry-based proteomics will be employed.

Required qualifications
- A PhD degree in cell biology, biochemistry, computational biology or related areas
- Background in hematology/oncology is advantageous
- Experience with cell culture, lentiviral shRNA/CRISPR screens and/or next-generation sequencing techniques
- At least one first author paper in a peer reviewed journal
- Knowledge of scripting languages such as Python or R is a plus, but not a prerequisite for the position
- Fluent in English with good writing skills
- Outstanding motivation and strong scientific enthusiasm to join a fast-moving and internationally competitive field

We offer
- The possibility to work on internationally competitive projects using state-of-the-art technologies
- A stimulating and international research environment
- Competitive salary (TV-GU E13, 100%)

To apply, please send a single PDF file containing the cover letter stating research and career interests, CV, contact addresses of at least two referees and certificates of your degrees to Dr. Sebastian Wagner (csb@med.uni-frankfurt.de). Informal inquiries are welcome. The Goethe-University Frankfurt is an equal opportunity employer.

Starting date: 1st March 2016 or later
Duration: Initially 2 years with an option of further extension

Sebastian Wagner
csb@med.uni-frankfurt.de
Goethe University
Frankfurt

Ansprechpartner: Sebastian Wagner