SCIENCE-JOBS-DE

Early Stage Researcher PhD Fellowship (Frankfurt)

The Department of Haematology/Oncology (Prof. Hubert Serve) at the Goethe-
University Frankfurt (Faculty of Medicine) is seeking a

PhD student (m/f)
(Early Stage Researcher PhD Fellowship)

within the framework of the Horizon 2020 Marie Curie European Training Network (ETN)
HaemMetabolome

Project 9: Hypoxia-induced metabolic shifts in Acute Myeloid Leukemia

starting from September 2016 but not later than December 2016.with a secondment at
the University of Barcelona, Spain

The aim of HaemMetabolome is to take the next steps to understand the cell biological
consequences of the genetic alterations that occur in the cells of several acute
haematological malignancies (Acute Myeloid Leukaemia (AML) and Chronic Myeloid
Leukaemia (CML) and multiple myeloma) and understand how these can be used to
improve treatment options. Resistance to existing therapies is frequently observed for
these diseases, and they remain incurable for the majority of cases. HaemMetabolome
will provide research training in the molecular mechanisms underlying the pathogenesis
of these cancers. The project 9 (ESR 10) will involve the use of a wide range of
experimental techniques including molecular biological (Western blot, RT-PCR), cell
biological (CRISPR/Cas9, SILAC) and in vitro assays (SeaHorse measurements, NMR)
and research using various AML mouse models.

HaemMetabolome has 10 Marie Curie Early Stage Researcher Fellowships funded, as
part of the Initial Training Network - European Joint Doctorate scheme. Researchers
employed on one of these Fellowships will be enrolled for 3 years on a dual PhD
programme between two of the HaemMetabolome partners, spending part of their
fellowships working at both partners.

For the mentioned project the candidate will be trained approx. 24 month at the
Goethe-University Frankfurt in Germany (Prof. Hubert Serve) with secondment (up to 12
 month) at the University of Barcelona (Prof. Marta Cascante).

Benefits: Candidates are paid according to Marie Curie standards, providing a
generous employment contract along with further support for research, training and
career development. Fellowships for Early Stage Researchers (ESRs) are fundable for
up to three-year periods.

Requirements: Outstanding ESRs must fulfil the Marie Curie eligibility criteria. ESRs are
required to have obtained a Master`s degree in biology, biochemistry or life sciences
within the last 4 years. They must also not be resided in Germany for more than 12
months in the last 3 years. Please visit the Marie Curie Web site for more details. For
citizens from non-EU countries specific immigration formalities and rules are in place.
Equal consideration will be given to female and male applicants. We are seeking an
ambitious, highly qualified and motivated student with a strong interest in biomedical
research. We expect the successful candidate to demonstrate prior knowledge and
experience of the aforementioned techniques. The ability to both work independently
and to contribute effectively to group projects, as well as an excellent command of IT
and of the English language are part of the basic prerequisites.

For further information: http://beregond.bham.ac.uk/~katkins/HaemMetabolome/


Applicants should submit their CV,certificates, letters of recommendation/references to
PD Dr. Frank Schnuetgen (schnuetgen@em.uni-frankfurt.de)
CC: Dr. Nina Kurrle (kurrle@med.uni-frankfurt.de)

Dr. Nina Kurrle
kurrle@med.uni-frankfurt.de
Goethe-University
Frankfurt