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Research Fellow: Edinburgh, United Kingdom

Research Fellow
£32,004 – £38,183

Multidisciplinary Research Project between: The Roslin Institute, MRC Centre for Regenerative Medicine and MRC Human Genetics Unit

Applications are invited for a postdoctoral fellowship to work on an exciting project investigating novel epigenetic regulators of cancer stem cell functions. This project will involve multidisciplinary approaches spanning stem cell and cancer biology, chromatin biology, genomics, precision medicine and computational biology. The postholder will be co-supervised by Dr Douglas Vernimmen (The Roslin Institute), Prof. Kamil R Kranc (MRC Centre for Regenerative Medicine) and Prof. Chris Ponting (MRC Human Genetics Unit). This multidisciplinary project will focus on polycomb pathways of haematopoietic stem cell (HSC) functions and the role of these pathways in leukaemic stem cell behaviour. We intend to utilise this knowledge in the development drug discovery in cancer/leukaemic stem cells.

The applicants should have PhD in life sciences. Expertise in mouse genetics, cell & molecular biology approaches will be an advantage. Excellent communication and interpersonal skills and the ability to work as part of a team as well as semi-independently are crucial.

Requests for further particulars and informal enquiries are encouraged and should be sent to Dr Douglas Vernimmen (Email: douglas.vernimmen@roslin.ed.ac.uk) and Prof. Kamil R Kranc (Email: kamil.kranc@ed.ac.uk).

For further information about the laboratory please visit: http://www.crm.ed.ac.uk/research/group/haematopoietic-stem-cells-and-leukaemia
http://www.roslin.ed.ac.uk/doug-vernimmen/summary-of-research/
http://www.hgu.mrc.ac.uk/people/chris.ponting_researchb.html

Selected publications:
Vernimmen et al., Genes & Dev. 25, 1583-1588 (2011)
Vukovic/Guitart, J. Exp. Med. 212, 2223-2234 (2015)
Guitart et al, Blood 122: 1741-1745 (2013)
Mortensen et al, J. Exp. Med. 208:455-467 (2011)
Kranc et al, Cell Stem Cell 5:659-665 (2009)

Ref: 038224 Closing Date: 27 January 2017

This post is available on a fixed term basis for 3 years.
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Employer:University of Edinburgh

Website:http://www.ed.ac.uk

Location:Edinburgh, United Kingdom

Expires:January 27, 2017

Job type:Postdoctoral

Salary:Unspecified

Qualifications:Postgraduate - Doctorate/PhD

Employment type:Contract

Job hours:Full-time