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Publish date: 96 / 05 / 02 | Rating: Article Rating

www.nature.com/naturejobs

Postdoctoral and Research Scientist Positions in Antibody Engineering: New York, NY, United States

Memorial Sloan Kettering Cancer Center

The research team led by Nai-Kong V. Cheung MD PhD works on developing the next generation of antibody therapeutics to treat pediatric and adult tumors. Several strategies are utilized to enhance anti-tumor potency, including the use of T cell engaging bispecific antibody formats and novel methods to enhance cytotoxic payload delivery. Antibody therapeutics are optimized using experimental techniques (phage and yeast display), recombinantly expressed and purified, tested for binding and stability by biophysical methods (biacore, SEC-HPLC, calorimetry), tested for in vitro potency on cell culture models, and then tested for in vivo potency in mouse xenograft models. This laboratory collaborates with other researchers at MSK in cell therapy and in nuclear medicine. Several projects involve academic/industry partnerships with the goal of generating lead candidates for first-in-human trials. The goal of the post-doctoral training is to prepare trainees for either academic or industrial careers.

Qualifications: PhD in biochemistry, immunology, biology or related biomedical science field and relevant experience. Successful track record documented by publications in high-impact international peer-reviewed journals.

Please send your cover letter, curriculum vitae and bibliography, including reprints of prior publications, and at least three letters of recommendation to Cheungn@mskcc.org

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

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Employer:Memorial Sloan Kettering Cancer Center (MSKCC)

Website:https://www.mskcc.org/

Location:New York, NY, United States

Expires:September 18, 2017

Job type:Postdoctoral

Salary:Unspecified

Qualifications:Postgraduate - Doctorate/PhD

Employment type:Unspecified

Job hours:Unspecified

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