The Institute for Clinical Chemistry at the University Medical Center Hamburg-Eppendorf offers a PhD position in Vascular Biology.

Our research aims to characterize the role of Neutrophil Extracellular Traps (NETs) in thrombosis. NETs are composed of extracellular DNA fibers and liberated from neutrophil granulocytes during inflammation. We have shown recently that NETs contribute to thrombosis in animals and biomarkers of NETs are associated with cardiovascular diseases in patients. Mechanistically, NETs appear to serve as an adhesive scaffold for blood cells and clotting factors, as well as triggering activation of platelets and coagulation. However, the molecular mechanisms are not fully understood (reviewed in Fuchs et al. ATVB 32 (8), 1777, 2012). To characterize the role of NETs in thrombosis, the successful candidate will be using in vitro assays and murine models combined with state-of-the-art molecular biology methods, imaging devices and high-throughput technology.

In summation, we are looking for an outstanding and highly motivated candidate with the following qualifications:

- MSc or diploma in biology, biochemistry, immunology or a related field
- Strong academic record and knowledge in molecular biology, cell biology and immunology
- Strong interest in inflammation, innate immunity and vascular biology
- Experience in basic science research and/or translational medicine
- Experience in cell culture, microscopy and murine disease models is a plus
- Proficiency in English is a must

Research will be conducted in the laboratories of the Institute for Clinical Chemistry located in the new research building of the University Medical Center Hamburg-Eppendorf, which provides an outstanding infrastructure with a wide range of core facilities.

The successful candidate will enroll in the PhD program at the Medical Faculty of Hamburg University, which offers an excellent educational framework for students with basic science and medical background. For further information visit: http://www.phd-medical-faculty-hamburg.de

Please submit your curriculum vitae, a statement of your research interests and the names and contact information of two academic references in electronic form to:

Tobias A. Fuchs, PhD
Assistant Professor
University Medical Center Hamburg-Eppendorf
Department of Clinical Chemistry / Central Laboratories
Martinistraße 52, 20246 Hamburg, Germany
E-Mail: t.fuchs@uke.de

Salary and benefits are according to a public service position in Germany (TV-KAH E13, 50%). The position is for 3 years and available immediately.

The University Medical Center Hamburg-Eppendorf supports equal employment opportunities. Preference will be given to female applicants or severely handicapped persons with equal qualifications.

Job details

Employer:University Medical Center Hamburg-Eppendorf, Germany

Location:’Hamburg, Hamburg, Germany

Expires:August 31, 2013

Job type:PhD Studentship

Salary:Unspecified

Qualifications:Postgraduate - Master's degree

Employment type:Contract

Job hours:Full-time

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