Subjects: Biology
Theme: Thesis: Tumor Biology: Cell fate control by the p53 signaling pathway
Contact: Dr. rer. nat. Thomas Hofmann
Reply to: t.hofmann @ dkfz.de
Institution: German Cancer Research Center (dkfz.)
Location: D-69120 Heidelberg, Im Neuenheimer Feld 280

We are looking for exceptional candidates in the field of tumor biology particularly focusing on kinase signalling pathways in response to DNA damage in cancer cells and (cancer) stem cells. The projects aim to elucidate novel molecular mechanisms of cell fate control after DNA damage.

Candidates should hold a MSc in Biology, Biotechnology, Biochemistry or Molecular Medicine. Applicants should have experience in molecular biology and cell biology. Knowledge of the German language is advantageous but not essential. Good written and spoken English skills and the capability for interaction and team work are required.

The research project is embedded in the Collaborative Research Center 1036 (SFB 1036). The successful candidate will be integrated in the Helmholtz International Graduate School at the Cancer Center at the DKFZ.

Methoden:
Cell Biology
Molecular Biology
Biochemistry
RNA Seq
ChIP Seq
Mouse model

Start date: 1 January 2014

Estimated duration: 3 years

Payment: TVL 13/2

Veröffentlichungen:
Bitomsky et al. and TG Hofmann, PNAS, 2013, in press.
Bitomsky N.and TG Hofmann, BioEssays, 2013.
Crone et al. and TG Hofmann, Cancer Research, 2011.
Winter, M et al. and TG Hofmann, Nature Cell Biol., 2008.

Homepage: http://www.dkfz.de/en/cellular_senescence/index.php

Applications (a single PDF file with full CV + certificates, brief outline of research competence and names of references) should be sent by November 5th, 2013 to Dr. Thomas Hofmann. Please apply by E-mail only, since documents will not be returned.