SCIENCE-JOBS-DE

Neuroscience - Pain mechanisms and inhibition (Berlin, Germany)

Postdoctoral positions in

PAIN RESEARCH / NEUROSCIENCE / PHARMACOLOGY

Department of Anesthesiology
Charité - Campus Benjamin Franklin
Freie Universität Berlin, Germany

Our group is interested in translational research on mechanisms of inflammatory and neuropathic pain and their control by opioids and neuro-immune interactions (e.g. Nature Med 2003;8:1003-8; J Neurosci 2006;26:4350-8; J Clin Invest 2008;118:1065-73; PLoS Pathog 2009,e1000362; J Clin Invest 2009,119:278-86; Pharmacol Rev 2011;63:860-81; FASEB J 2012;26:5161-71; EMBO Mol Med 2013,5:1263-77).

We are funded by the Deutsche Forschungsgemeinschaft (DFG), the Bundesministerium für Bildung und Forschung (BMBF), the European Commission, and the Helmholtz Virtual Institute for Biomaterials in Medicine, and provide a stimulating environment through interactions with experimental and clinical groups at the Freie Universität Berlin, Charité, Max-Planck Institute for Molecular Genetics, Zuse Institute for Applied Mathematics, Deutsches Rheuma-Forschungszentrum, Leibniz Institute for Molecular Pharmacology, and Max-Delbrück Center for Molecular Medicine.

We are seeking candidates with expertise in electrophysiology (e.g. in vitro skin-nerve preparation, patch clamp), immunohistochemistry/immunofluorescence, in situ hybridization, and/or in vivo behavioral testing in rodent models of inflammatory and neuropathic pain (e.g. paw pressure, von Frey, Hargreaves, CatWalk tests).

The postdoctoral positions are part of multidisciplinary projects on the computational design, chemical, immune, and genetic modulation of opioids for inflammatory and neuropathic pain. All necessary equipment is available, including in vitro skin-nerve preparation, patch clamp, cell culture, calcium and potassium imaging, immunohistochemistry/immunofluorescence, Western blotting, radioimmuno-/enzyme assays, binding, PCR, cloning, mutagenesis, FACS, MACS, in vivo microdialysis, in vivo testing of pain, sedation, respiratory depression, place preference conditioning, and clinical measurement of pain in human patients. Establishment of new strategies and methods is encouraged.

Successful applicants will be highly motivated, career-focused individuals who are self starters, comfortable in carrying out research both individually and in a team, prepared to work on schedules requiring intermittent evenings, weekends and/or holidays as needed, able to design, execute, analyze, and professionally write up research projects and animal ethics protocols. Demonstrated proficiency in English language is required; proficiency in German language is desirable. Applications require a completed PhD or equivalent degree in biology, neuroscience, biochemistry, pharmacology, or related fields. The positions are available for 3 years, beginning April or May, 2014. Salary is according to E 13. We cannot reimburse travel expenses for applicants. Please send CV and names of two references to:

Prof. Dr. Halina Machelska
Department of Anesthesiology
Charité - Campus Benjamin Franklin
Hindenburgdamm 30
D-12203 Berlin, Germany
Email: halina.machelska@charite.de
http://anaesthesie.charite.de/

Halina Machelska
halina.machelska@charite.de
Charité - Campus Benjamin Franklin, Department of Anesthesiology
Berlin, Germany