SCIENCE-JOBS-DE

Master thesis projects (salaried) in (patho)physiology of atherosclerosis and metabolic diseases (Homburg)

Several master thesis projects are available at the Saarland University Medical Center  (Dpt. Internal Med. II) in Homburg /Saar:

1. Characterization of the role of the redox sensor DJ-1 (Park7) in metabolic and vascular disease. It is planned to study the phenotype of a diet induced metabolic phenotype in DJ-1 KO mice in vivo. The mechanism of the observed pathophysiology will be elucidated in primary cells harvested from such animals.

2. Studying the role of immune response gene 1 (IRG1) in bone disease and bone metastasis. IRG1 has unexpectedly found to be expressed in osteoclasts. Its function remains elusive in this context. Osteoclast (OC) are a major cell type contributing to bone loss in  osteoporosis as well as in metastatic bone disease (vicious cycle of skeletal metastasis). We aim to characterize the effect of IRG1 on OC function in vivo. In addition, a potential contribution of IRG1 in bone pathology will be studied in vivo.


All master thesis projects will be conducted in a collaborative setting between the Saarland University Medical Center and the University of Luxembourg (LCSB). The latter is a provider for high throughput methodologies that will be employed.

We offer a certain level of PAYMENT for the master thesis projects. In addition, a structured career planning is offered, e.g. help in applying for a PhD position is included.

Interested candidates with an appropriate background and motivation are invited to contact Dr Jochen Schneider (jochen.schneider@uks.eu), Phone: 06841 1623242.


Jochen Schneider
jochen.schneider@uks.eu
Saarland University Medical Center
Homburg