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Publish date: 93 / 04 / 07 | Rating: Article Rating

http://www.nature.com/naturejobs/science

PhD in Neuroscience : Bochum, Germany

A PhD student position (4 years) is available in the Dept of Systems Neuroscience, led by Prof Patrik Krieger, at the Ruhr-University, Bochum, Germany. http://www.ruhr-uni-bochum.de/sysnw/index.html.en

The Ph D project will address questions pertaining to sensory processing, with a focus on the rodent whisker system. Behaviour guided by sensory stimuli depends on the interplay between movements of the sensory organ (e.g., rodent’s whiskers), cortical processing, and finally motor output that can cause adjustment of body position and sensory organ movements. This sensory-motor-sensory loop is dynamically regulated by cortical control of sub-cortical structures. Rodents extensively use their whiskers to form a representation of the external world. It remains unclear how this representation is affected by sensory-evoked modulation of motor outputs and by changes in sensory detection. To analyze the mechanisms underlying top-down modulation of sensory information transfer we will control, using optogenetics and other genetic technologies, the activity of cortical projection neurons to elucidate the contribution of specific cell populations. In particular the project will investigate how feedback from cortex controls sensory processing in sub cortical structures, such as striatum and thalamus. The aim is to analyze the importance of cortical projections to brain areas involved in sensory-guided behaviour, and cortical projections that modulate thalamic responses to optimize detectability. We investigate sensory processing using a variety of in vitro and in vivo electrophysiological methods and imaging techniques, including two-photon imaging. In particular we use genetic technologies in combination with optogenetics and behavioral assays to investigate the contribution of specific cell populations to sensory processing.

The successful candidate (Master or Diploma degree in Biology, Physics, Chemistry or Neuroscience) will benefit from being part of the neuroscience community at the Ruhr-University ( SFB 874 – http://www.ruhr-uni-bochum.de/sfb874/index_en.html ), and from national and international collaborations. The applicant can also take part in the PhD programme at the International Graduate School of Neuroscience (IGSN). IGSN offers an extensive curriculum with courses and symposiums. Link to IGSN: http://www.ruhr-uni-bochum.de/igsn/index.shtml

The Welcome Centre at the Ruhr University offers international student service and support finding accommodation, childcare etc. http://international.rub.de/welcomecentre/index.html.en

The position is paid according to a standard rate (E13 TV-L/65%) and is available for 4 years.

Please send your application via e-mail to ( sysnw@rub.de ) as one pdf including:
1. Personal statement of education and neuroscience interests
2. CV
3. Two letters of recommendation

Evaluation will start July 28 and remain open until the position is filled.

Job details

Employer:Ruhr-University Bochum (Ruhr-Universität Bochum) RUB

Website:http://www.ruhr-uni-bochum.de...

Location:Bochum, Germany

Expires:August 25, 2014

Job type:PhD Studentship

Salary:Unspecified

Qualifications:Undergraduate - Bachelor's degree

Employment type:Temporary

Job hours:Full-time

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